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WHAT YOU NEED TO KNOW ABOUT ANTIOXIDANTS & THEIR POWER OF PREVENTION



Oranges
This article originally appeared in the Spring 1996 issue of Optimum Nutrition Magazine.

DURING THE LAST DECADE MORE AND MORE RESEARCH HAS CONFIRMED THAT MANY OF THE 20TH CENTURY’S MOST COMMON DISEASES ARE ASSOCIATED WITH DEFICIENCY OF ANTIOXIDANT NUTRIENTS, AND HELPED BY THEIR SUPPLEMENTATION. A NEW MEDICAL MODEL IS EMERGING, THAT CONSIDERS THE PRESENCE O ANYONE OF THESE I DISEASES A SIGN OF PROBABLE ANTIOXIDANT DEFICIENCY, IN THE SAME WAY THAT SCURVY IS A SIGN OF VITAMIN C DEFICIENCY. IN THE FUTURE WE MAY BE TESTED FOR BLOOD LEVELS OF ANTIOXIDANT NUTRIENTS, ALONGSIDE BLOOD SUGAR, CHOLESTEROL AND BLOOD PRESSURE. CAPABLE OF PREDICTING YOUR BIOLOGICAL AGE, AND EXPECTED LIFESPAN, YOUR ANTIOXIDANT NUTRIENT STATUS MAY PROVE TO YOUR MOST VITAL STATISTIC. MEDICAL RESEARCHER, DR EMANUEL CHERASKIN, BRINGS US UP TO DATE WITH THE ROLE OF ANTIOXIDANTS IN HEALTH AND DISEASE.


The medical literature is replete with information which suggests that a common denominator in the ageing process and the diseases associated with ageing is ‘oxidative damage’. This has put the spotlight on the use of antioxidants, nutrients that help protect the body from this damage, in the prevention and treatment of disease. So far, over a hundred antioxidant nutrients have been discovered and hundreds, if not thousands of research papers have extolled their benefits. The main players are vitamins A, C and E, plus beta-carotene, the precursor of vitamin A found in fruits and vegetables. Their presence in your diet, and levels in your blood may prove the best marker yet of your power to prevent death and disease. Here, we show you how to test your Antioxidant Profile, and what steps you need to take to boost your power of prevention.


ANTIOXIDANT?

Oxygen is our most important nutrient, needed by every cell every second of every day. Without it we cannot release the energy in food which drives all body processes. Oxygen is chemically reactive and highly dangerous. In normal biochemical reactions oxygen can become unstable and capable of ‘oxidising’ neighbouring molecules. This can lead to cellular damage, triggering cancer, inflammation, arterial damage and ageing. Known as ‘free oxidising radicals’ this equivalent of ‘nuclear waste’ must be disarmed to remove the danger. Free radicals are made in all combustion processes including smoking, exhaust fumes, radiation, fried or barbecued food and normal body processes. Chemicals capable of disarming free radicals are called ‘antioxidants’. Some are known essential nutrients, like vitamins A & beta-carotene, C and E. Others are not essential as such, like bioflavonoids, anthocyanidins, pycnogenol and over 100 other recently identified protectors found in common foods.
The balance between your intake of antioxidants and exposure to free radicals may literally be the balance between life and death. You can tip the scales in your favour by simple changes to diet and antioxidant supplementation.

Your Personal ANTIOXIDANT Profile

TEST YOUR POWER OF PREVENTION


Symptom Analysis
  • Do you frequently suffer from infections (coughs, colds)?                                                                                
  • Do you find it hard to shift an infection?
  • Do you have a recurrent infection (cystitis, thrush, earaches etc.)?
  • Do you bruise easily?
  • Have you ever suffered from any of the conditions listed overleaf?
  • Have your parents collectively suffered from two or more of these conditions?
  • Do you easily get exhausted on physical exertion?
  • Does your skin take a long time to heal?
  • Do you suffer from acne, dry skin or excessive wrinkles for your age?
  • Are you overweight?
Add up your score out of 10. 1 for each ‘yes’.

Lifestyle Analysis

  • Have you smoked for more than 5 years of your life, less than 5 years ago?
  • Do you smoke now?                                                                                                    Do you smoke more than 10 cigarettes a day?
  • Do you spend time most days in a smoky atmosphere?
  • Do you have an alcoholic drink each day?
  • Do you live in a polluted city, or by a busy road?
  • Do you spend more than two hours in traffic each day?
  • Are you quite often exposed to strong sunlight?
  • Do you consider yourself unfit?
  • Do you exercise excessively and get easily ‘burnt out’?

Add up your score out of 10. 1 for each ‘yes’.

Diet Analysis

  • Do you eat fried food most days?
  • Do you eat less than two servings of vegetables each day?
  • Do you eat less than two pieces of fresh fruit a day?
  • Do you rarely eat nuts, seeds or wholegrains each day?
  • Do you eat smoked, barbecued food or grill cheese on your food?
  • Do you supplement less than 500mg of vitamin C each day?
  • Do you supplement less than 100iu of vitamin E each day?
  • Do you supplement less than I 0,000iu of vitamin A or beta-carotene each day?
  • Add up your score out of 10. 1 for each ‘yes’.

YOUR TOTAL SCORE
0-10 This is an IDEAL score, indicating that your health, diet and lifestyle are consistent with a high level of antioxidant protection. Keep up the good work!
11-15 This is a REASONABLE score, although you can increase your power of prevention by converting ‘yes’ answers into ‘no’.
16-20 This is a POOR score, indicating much room for improvement. See a nutritionist to upgrade your diet and lifestyle for increased antioxidant protection
20 + This is a BAD score, putting you in the high-risk group for rapid ageing. See a nutritionist and ask for an Antioxidant Profile blood test. You’ll need to make changes to your diet and lifestyle, plus supplement antioxidants to slow down the ageing process.

 
ANTIOXIDANT Profile
The best way to determine your antioxidant status is to have a biochemical Antioxidant Profile. This blood test measures the levels of beta-carotene, C and E in your blood and how well antioxidant enzyme systems are functioning. In all, nine measures of antioxidant status are measured, giving a comprehensive indication of your antioxidant status. Look out for a new, less expensive and extensive ‘TRAP’ test (total reactive antioxidant potential). This will indicative if there’s an antioxidant problem but doesn’t define which nutrients are missing.
The Antioxidant Profile is available on referral from doctors to Bio Lab, The Stone House, 30 Weymouth Street, London WIN 3FF Tel:017I-636 5959.  Ask your doctor to refer you.


ANTIOXIDANTS IN HEALTH & DISEASE: THE BIG PICTURE


ALZHEIMERS
Elderly people with Alzheimer's disease have lower blood vitamin A levels, half the vitamin E levels and less than half the beta-carotene levels of elderly people who donts.

CANCER
People with lung cancer have much lower blood vitamin A levels. Those with low dietary intake of vitamin A have double the risk of lung cancer than those with the highest vitamin A intake. Similarly, a high intake of beta-carotene from raw fruits and vegetables reduce the risk of lung cancer in nonsmoking men and women. Supplementing beta-carotene (30mg per day) resulted in 71% of patients with oral pre-cancer (leukoplakia) improving, while patients given 200,000iu of vitamin A a day resulted in 57% of patients having complete remission.

CATARACTS
People with low blood vitamin C levels have 11 times the risk of developing cataracts compared to those with high blood vitamin C levels. Similarly, those with low vitamin E blood levels had almost double the risk. People consuming 400ius of vitamin E a day have half the risk of cataracts.

HEART DISEASE AND HIGH BLOOD PRESSURE
The higher one’s vitamin A levels (63 to 83mp) and vitamin levels (0.7 to 0.9.ig%) in the blood; the lower one’s risk.  In the case of vitamin C; the lower one’s blood pressure. Nurses who consume 15 to 20mg per day of beta-carotene had 40% lower risk of stroke and 22% lower risk of a heart attack compared to those consuming 6mg per day. Those with high dietary intakes of beta-carotene halve their risk of death from cardiovascular disease. Supplementing 1600mg of vitamin E more than halved symptoms of heart disease. Supplementing 1000mg of vitamin C reduces blood pressure.

INFERTILITY
Supplementing 20 infertile men with 1000mg of vitamin C produced conception in all their couples within two months. Not so for those on placebo.

MACULAR DEGENERATION
People with macular (eye lens) degeneration have lower blood vitamin E and vitamin C levels. Those with high beta-carotene levels have half the risk.

MENTAL ILLNESS
The manic/depressive state of 24 people was vastly improved within hours of supplementing 3 grammes of vitamin C daily.

IMMUNITY AND INFECTIONS
Supplementing 800ius of vitamin E daily increases blood levels and immune response. Supplementing 180mg of beta-carotene daily increases immune response and T-cell count. Supplementing vitamin A (450mg per day) reduced the incidence of respiratory tract infections on pre-school children.

RHEUMATOID ARTHRITIS
Supplementing 1000ius of vitamin E reduced pain and stiffness in patients with rheumatoid arthritis.


ANTIOXIDANTS & SUPPLEMENTS
VITAMIN A The Suggested Optimal Nutrient Allowance per day for vitamin A and beta-carotene is 800 to 1000mcg RE (retinol equivalent) for children and 800-2000mcg RE for adults. We recommend supplementing between 2000mcg (6600iu) and 3000mcg (10,000iu) per day of retinol and the same again for beta-carotene.
VITAMIN C The Suggested Optimal Nutrient Allowance per day is 150mg for children and 400 to 1000mg for adults. We recommend supplementing between 1000 and 3,000mg per day.
VITAMIN E The Suggested Optimal Nutrient Allowance per day is 70mg for children and 90-800mg for adults. We recommend supplementing between 400 and 800 mg per day (roughly equivalent to 400 to 800ius).
Many other diseases not listed here, including colds, diabetes, HIV infection, measles, periodontal disease and chronic fatigue syndrome.

FOOD
The best all-round antioxidant foods have the highest * rating. Foods are listed in order of their * rating. Make sure these foods form a large part of your diet.

Rich source ofACE
Sweet potato*******
Carrots******
Watercress******
Peas*****
Broccoli*****
Cauliflower****
Lemons****






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