The Institute for Optimum Nutrition
Betaine hydrochloride is an acidic form of betaine, a vitamin-like substance found in grains and other foods. Betaine hydrochloride is recommended by some doctors as a supplemental source of hydrochloric acid for people who have a deficiency of stomach acid production (hypochlorhydria).
Gastric acid is produced by the parietal cells of the stomach. The acidity is quite strong in a normal stomach. In fact, the stomach can be between 100,000 and almost 1,000,000 times more acidic than water.
Betaine hydrochloride (HCl) has been used in connection with the following conditions (refer to the individual health concern for complete information):
| Science Ratings | Health Concerns |
|---|---|
 |
Gastroesophageal reflux disease (GERD) Iron-deficiency anemia (as an adjunct to supplemental iron) Tic douloureux |
 Reliable
and relatively consistent scientific data showing a substantial health benefit. Contradictory, insufficient, or preliminary studies
suggesting a health benefit or minimal health benefit. For an herb, supported by traditional use but minimal
or no scientific evidence. For a supplement, little scientific support and/or minimal health
benefit. |
|
Some research suggests that people with a wide variety of chronic disorders, such as allergies,1 asthma,2 and gallstones,3 do not produce adequate amounts of stomach acid.
Betaine HCl is the most common hydrochloric acid-containing supplement. Normally it comes in tablets or capsules measured in grains or milligrams. Only people who have reduced levels of stomach acid (“hypochlorhydria”) should take betaine HCl; this condition can be diagnosed by a doctor. When appropriate, some doctors recommend taking one or more tablets or capsules, each 5–10 grains (325–650 mg), with a meal that contains protein. Occasionally, betaine (trimethylglycine) is recommended to reduce blood levels of a substance called homocysteine, which is associated with heart disease. This form of betaine is different from betaine HCl.
Large amounts of betaine HCl can burn the lining of the stomach. If a burning sensation is experienced, betaine HCl should be immediately discontinued. People should not take more than 10 grains (650 mg) of betaine HCl without the recommendation of a physician. All people with a history of peptic ulcers, gastritis, or gastrointestinal symptoms—particularly heartburn—should see a doctor before taking betaine HCl. People taking nonsteroidal anti-inflammatory drugs (NSAIDs), cortisone-like drugs, or other medications that might cause a peptic ulcer should not take betaine HCl. Betaine HCl helps make some minerals and other nutrients more absorbable.4 5
At the time of writing, there were no well-known drug interactions with Betaine Hydrochloride.
Copyright © 2009 Aisle7 All rights reserved. www.Aisle7.net
Learn more about the authors of Aisle7 products.
The information presented in Aisle7 is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or chemist for any health problem and before using any supplements or before making any changes in prescribed medications.
* General Disclaimer - Information and advice provided by The Institute for Optimum Nutrition is not intended as a substitute for medical advice. Anyone suffering from a condition that requires medical attention or has symptoms that concerns them, should consult a qualified medical practitioner.ION and its staff shall not be held responsible for any claims relating to illness or ailments that are deemed to have arisen as a consequence of reading any part, or all of the content provided on this website. The content is provided for general use and may be unsuitable for people suffering from conditions, diagnosed or otherwise. The Institute for Optimum
Nutrition is an independent educational charity, registered charity number 1013084.
Top