The Institute for Optimum Nutrition
Lipase is an enzyme that is used by the body to break down dietary fats into an absorbable form.
Most of the body’s lipase is manufactured in the pancreas, although some of it is secreted in the saliva, as well. Pancreatin contains lipase along with two other groups of enzymes: proteases and amylase.
Lipase has been used in connection with the following conditions (refer to the individual health concern for complete information):
| Science Ratings | Health Concerns |
|---|---|
 |
|
 |
Indigestion (for pancreatic insufficiency only) |
 |
|
| Reliable
and relatively consistent scientific data showing a substantial health benefit. Contradictory, insufficient, or preliminary studies
suggesting a health benefit or minimal health benefit. For an herb, supported by traditional use but minimal
or no scientific evidence. For a supplement, little scientific support and/or minimal health
benefit. |
|
People with pancreatic insufficiency and cystic fibrosis frequently require supplemental lipase and other enzymes. In addition, those with celiac disease1 or Crohn’s disease2 and perhaps some people suffering from indigestion3 may be deficient in pancreatic enzymes including lipase.
Products that contain lipase also usually contain other enzymes that help digest carbohydrates and protein. In the U.S., pancreatin, which contains lipase, amylase, and proteases, is rated against a government standard. For example, “9X pancreatin” is nine times stronger than the government standard. Each “X” contains 25 USP units of amylase, 2 USP units of lipase, and 25 USP units of proteolytic enzymes. Taking 1.5 grams of 9X pancreatin (or a higher amount at lower potencies) with each meal can help people with pancreatic insufficiency digest food.
Lipase does not generally cause any side effects at the amounts listed above.
At the time of writing, there were no well-known drug interactions with lipase.
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The information presented in Aisle7 is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or chemist for any health problem and before using any supplements or before making any changes in prescribed medications.
* General Disclaimer - Information and advice provided by The Institute for Optimum Nutrition is not intended as a substitute for medical advice. Anyone suffering from a condition that requires medical attention or has symptoms that concerns them, should consult a qualified medical practitioner.ION and its staff shall not be held responsible for any claims relating to illness or ailments that are deemed to have arisen as a consequence of reading any part, or all of the content provided on this website. The content is provided for general use and may be unsuitable for people suffering from conditions, diagnosed or otherwise. The Institute for Optimum
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